BDBM350120 5-(3-chlorobenzyl)-1-(2- hydroxyethyl)-1H- pyrazol[3,4-d]pyrimidin- 4(5H)-one::US10208043, # 21::US10941146, # 21

SMILES OCCn1ncc2c1ncn(Cc1cccc(Cl)c1)c2=O

InChI Key InChIKey=ICHYYMIZHQCJKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350120   

TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350120(5-(3-chlorobenzyl)-1-(2- hydroxyethyl)-1H- pyrazol...)
Affinity DataIC50:  1.20E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350120(5-(3-chlorobenzyl)-1-(2- hydroxyethyl)-1H- pyrazol...)
Affinity DataIC50:  1.20E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent