BDBM350127 5-(2-(benzo[d][1,3]dioxol- 5-yl)-2-oxoethyl)-1-(S,S- dioxo-tetrahydrothiophen- 3-yl)-1H-pyrazolo[3,4- d]pyrimidin-4(5H)-one::US10208043, # 29::US10941146, # 29

SMILES O=C(Cn1cnc2n(ncc2c1=O)C1CCS(=O)(=O)C1)c1ccc2OCOc2c1

InChI Key InChIKey=AFQKGJUEYFWDSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350127   

TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350127(5-(2-(benzo[d][1,3]dioxol- 5-yl)-2-oxoethyl)-1-(S,...)
Affinity DataIC50:  3.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350127(5-(2-(benzo[d][1,3]dioxol- 5-yl)-2-oxoethyl)-1-(S,...)
Affinity DataIC50:  3.70E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent