BDBM350300 US10208064, Example 19
SMILES C[C@H]1CC2(CCN(C[C@@H](O)c3ccc4c(ccc5nnnn45)c3)CC2)C(=O)N1C1=CC(=O)OC1
InChI Key InChIKey=SUFBPVQFOFQPFD-MGPUTAFESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 350300
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
US Patent
Wuxi Apptec (Shanghai)
US Patent
Affinity DataIC50: 10nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair