BDBM350527 N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.5]dec-3-yl)acetamide::US10208071, Table 3.3::US10434112, Table 3.3::US10799518, Structure TABLE 3.3

SMILES Brc1ccc(NC(=O)CN2C(=O)NC3(CCCCC3)C2=O)cc1

InChI Key InChIKey=UUIRITXPYAOMCC-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 350527   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350527(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.5...)
Affinity DataEC50:  7.38E+5nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350527(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.5...)
Affinity DataEC50:  738nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350527(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.5...)
Affinity DataEC50:  738nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Suez Canal University

Curated by ChEMBL
LigandPNGBDBM350527(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.5...)
Affinity DataIC50:  720nMAssay Description:Inhibition of ALR2 (unknown origin) using sodium dl-glyceraldehyde as substrate preincubated for 10 mins followed by substrate addition by UV-spectro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Suez Canal University

Curated by ChEMBL
LigandPNGBDBM350527(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.5...)
Affinity DataIC50:  3.12E+4nMAssay Description:Inhibition of ALR1 (unknown origin) using sodium d-glucoronate as substrate preincubated for 10 mins followed by substrate addition by UV-spectrophot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed