BDBM350856 UNC2146A::US10004755, Compound UNC2146A::US9795606, B15
SMILES CCCCNc1ncc2c(cn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)N1CC(F)(F)C1
InChI Key InChIKey=VZHCQBXYACZHPJ-HSNGWXBGSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 350856
Affinity DataIC50: <250nMAssay Description:The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Human)
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 38nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina At Chapel Hill
US Patent
University of North Carolina At Chapel Hill
US Patent
Affinity DataIC50: 31nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition constants of MerTK, Flt3, Tyro3 and Axl kinase activity by an active compound as described herein is determined at the Km for ATP using a ...More data for this Ligand-Target Pair