BDBM351476 1,1-dimethylethyl 2-[3-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,2,4- oxadiazol-5-yl]piperidine-1-carboxylate::US9796704, Entry 196

SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCCCN1C(=O)OC(C)(C)C

InChI Key InChIKey=RUBSXJGCJAOKHK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 351476   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351476(1,1-dimethylethyl 2-[3-({[4-[(3,4- dichlorophenyl)...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351476(1,1-dimethylethyl 2-[3-({[4-[(3,4- dichlorophenyl)...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351476(1,1-dimethylethyl 2-[3-({[4-[(3,4- dichlorophenyl)...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351476(1,1-dimethylethyl 2-[3-({[4-[(3,4- dichlorophenyl)...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351476(1,1-dimethylethyl 2-[3-({[4-[(3,4- dichlorophenyl)...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent