BDBM351478 N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (4-pyrrolidin-1-ylphenyl)-1,3-thiazol-2- yl]methyl}oxy)quinazolin-4-amine::US9796704, Entry 198

SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(cs1)-c1ccc(cc1)N1CCCC1

InChI Key InChIKey=LARWQCXRXJJFLU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 351478   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351478(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (4-py...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351478(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (4-py...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351478(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (4-py...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351478(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (4-py...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351478(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (4-py...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent