BDBM351985 1-(2-((1R,3S,5R)-3-(6- bromopyridin-2- ylcarbamoyl)-2- azabicyclo[3.1.0]hexan- 2-yl)-2-oxoethyl)-5- (pyrimidin-5-yl)-1H- indazole-3-carboxamide::US10287301, Compound 4::US10822352, Comp No. 4::US9796741, cmp No. 4

SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(cc12)-c1cncnc1

InChI Key InChIKey=UEOSELNXXJLLHW-ZMYBRWDISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 351985   

TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM351985(1-(2-((1R,3S,5R)-3-(6- bromopyridin-2- ylcarbamoyl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM351985(1-(2-((1R,3S,5R)-3-(6- bromopyridin-2- ylcarbamoyl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM351985(1-(2-((1R,3S,5R)-3-(6- bromopyridin-2- ylcarbamoyl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent