BDBM352660 US9802960, Compound I-238

SMILES Cc1ncc(c(C)c1NS(=O)(=O)c1ccc(F)cc1F)-c1ccnc(Nc2ccc(C#N)c(C)n2)c1

InChI Key InChIKey=HKYDPVVTYYURLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352660   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM352660(US9802960, Compound I-238)
Affinity DataIC50: <10nMAssay Description:100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent