BDBM35528 symmetric dicoumarol analogue, 4

SMILES COc1ccc2oc(=O)c(Cc3c(O)c4cc(OC)ccc4oc3=O)c(O)c2c1

InChI Key InChIKey=VISBUWIQAVVPBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35528   

TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35528(symmetric dicoumarol analogue, 4)
Affinity DataIC50:  11nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University of Manchester

LigandPNGBDBM35528(symmetric dicoumarol analogue, 4)
Affinity DataIC50:  3.30E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed