BDBM355678 1-{2-[(1R,3S,5R)-3-((1R,2R)-2- Fluoro-2-phenyl- cyclopropylcarbamoyl)-2-aza- bicyclo[3.1.0]hex-2-yl]-2-oxo-ethyl}- 1H-pyrazolo[3,4-c]pyridine-3- carboxylic acid amide::US9815819, 43

SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@@H]2C[C@@]2(F)c2ccccc2)c2cnccc12

InChI Key InChIKey=YSHYEVNFHXZBHT-RYHISXGPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355678   

TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM355678(1-{2-[(1R,3S,5R)-3-((1R,2R)-2- Fluoro-2-phenyl- cy...)
Affinity DataIC50:  214nMAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent