BDBM356571 N-[3-(7-{1-[1-Methyl-2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-pyrazol-4-yl}imidazo[1,2-b]pyridazin-3-yl)phenyl]-N′-(2,2,2-trifluoroethyl)urea::US10213427, Example 60::US10813930, Ex. No. 60
SMILES CC(N\C=C(/C=N)c1cnn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1)C(=O)N1CCN(C)CC1
InChI Key InChIKey=BGLVQKSOSREIHX-BZPXYCMESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 356571
Affinity DataIC50: <10nMAssay Description:FGFR3 Enzymatic Assay The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to ...More data for this Ligand-Target Pair