BDBM357631 7-(4- methylbenzyl)- 3H- [1,2,3]triazolo [4,5-b]pyridin- 5-amine::US10214527, Example 3::US10214527, Example 4

SMILES COc1ccc(Cc2cc(N)nc3[nH]nnc23)cc1

InChI Key InChIKey=STKBZTLIQVHPGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357631   

TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM357631(7-(4- methylbenzyl)- 3H- [1,2,3]triazolo [4,5-b]py...)
Affinity DataIC50:  500nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM357631(7-(4- methylbenzyl)- 3H- [1,2,3]triazolo [4,5-b]py...)
Affinity DataIC50:  500nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent