BDBM357661 7-(2,6- difluorobenzyl)- 3H-[1,2,3] triazolo[4,5- b]pyridin-5- amine::US10214527, Example 33

SMILES Nc1cc(Cc2c(F)cccc2F)c2nn[nH]c2n1

InChI Key InChIKey=QEWIOOMOXLQDHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357661   

TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM357661(7-(2,6- difluorobenzyl)- 3H-[1,2,3] triazolo[4,5- ...)
Affinity DataIC50:  55nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent