BDBM360103 (1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-::US10221162, Example 400.0::US10221162, Example 401.0::US10221162, Example 402.0::US10221162, Example 403.0

SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](OC[C@@H](C)O)c2ncc(C)cn2)nnc1-c1cncc(C)c1

InChI Key InChIKey=ZRYDYSLVRCAKOO-IMWIBFENSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 360103   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360103((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  17nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360103((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  0.210nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360103((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  0.860nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360103((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  21nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent