BDBM360117 (2S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-ethyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-(5-::US10221162, Example 418.0::US9845310, Example 420.0

SMILES CCc1cncc(c1)-c1nnc(NS(=O)(=O)[C@H](C)Cc2ncc(F)cn2)n1-c1c(OC)cccc1OC

InChI Key InChIKey=JZKHWHWVLNGDPV-OAHLLOKOSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 360117   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360117((2S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-ethyl-3-pyrid...)
Affinity DataEC50:  6.30nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360117((2S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-ethyl-3-pyrid...)
Affinity DataEC50:  7.90nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent