BDBM360138 (1R,2R)-1-cyclohexyl-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridinyl)-4H-::US10221162, Example 441.0

SMILES COc1cccc(n1)-c1nnc(N(CC[Si](C)(C)C)S(=O)(=O)[C@@H](C)[C@H](O)C2CCCCC2)n1-c1c(OC)cccc1OC

InChI Key InChIKey=WPXNFMQPGMQVII-KMRXNPHXSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360138   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360138((1R,2R)-1-cyclohexyl-N-(4-(2,6-dimethoxyphenyl)-5-...)
Affinity DataEC50:  1.20nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent