BDBM360850 4-(2-amino-7- methylbenzo[d]thiazol-4-yl)- 3-(2H-tetrazol-5-yl)benzene- 1,2-disulfonamide::US10221163, Example 6::US10544130, Example 6

SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(N)(=O)=O)c2nc(N)sc12

InChI Key InChIKey=CRWZLJNNDOWHSX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 360850   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360850(4-(2-amino-7- methylbenzo[d]thiazol-4-yl)- 3-(2H-t...)
Affinity DataIC50:  0.0650nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360850(4-(2-amino-7- methylbenzo[d]thiazol-4-yl)- 3-(2H-t...)
Affinity DataIC50:  0.0270nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase()
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360850(4-(2-amino-7- methylbenzo[d]thiazol-4-yl)- 3-(2H-t...)
Affinity DataIC50:  0.0910nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360850(4-(2-amino-7- methylbenzo[d]thiazol-4-yl)- 3-(2H-t...)
Affinity DataIC50:  0.0650nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360850(4-(2-amino-7- methylbenzo[d]thiazol-4-yl)- 3-(2H-t...)
Affinity DataIC50:  0.0270nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360850(4-(2-amino-7- methylbenzo[d]thiazol-4-yl)- 3-(2H-t...)
Affinity DataIC50:  0.0910nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent