BDBM360985 4'-((4R,5S)-4-methyl-2- oxooxazolidin-5-yl)-N4-((R)- pyrrolidin-3-yl)-2-(1H-tetrazol- 5-yl)-[1,1'-biphenyl]-3,4- disulfonamide::US10221163, Example 141::US10544130, Example 141

SMILES C[C@H]1NC(=O)O[C@H]1c1ccc(cc1)-c1ccc(c(c1-c1nnn[nH]1)S(N)(=O)=O)S(=O)(=O)N[C@@H]1CCNC1

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 360985   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360985(4'-((4R,5S)-4-methyl-2- oxooxazolidin-5-yl)-N4-((R...)
Affinity DataIC50:  0.0410nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360985(4'-((4R,5S)-4-methyl-2- oxooxazolidin-5-yl)-N4-((R...)
Affinity DataIC50:  0.0190nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase()
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360985(4'-((4R,5S)-4-methyl-2- oxooxazolidin-5-yl)-N4-((R...)
Affinity DataIC50:  0.0620nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360985(4'-((4R,5S)-4-methyl-2- oxooxazolidin-5-yl)-N4-((R...)
Affinity DataIC50:  0.0410nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360985(4'-((4R,5S)-4-methyl-2- oxooxazolidin-5-yl)-N4-((R...)
Affinity DataIC50:  0.0190nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360985(4'-((4R,5S)-4-methyl-2- oxooxazolidin-5-yl)-N4-((R...)
Affinity DataIC50:  0.0620nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent