BDBM361025 4-(2-amino-1H-benzo[d]imidazol-4-yl)-N1-(3-aminopropyl)-3-(2H-tetrazol-5-yl)benzene-1,2-disulfonamide::US10221163, Example 182::US10544130, Example 182

SMILES NCCCNS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key InChIKey=BFOYHAUOQCJINB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 361025   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361025(4-(2-amino-1H-benzo[d]imidazol-4-yl)-N1-(3-aminopr...)
Affinity DataIC50:  0.453nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361025(4-(2-amino-1H-benzo[d]imidazol-4-yl)-N1-(3-aminopr...)
Affinity DataIC50:  0.0390nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase()
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361025(4-(2-amino-1H-benzo[d]imidazol-4-yl)-N1-(3-aminopr...)
Affinity DataIC50:  0.0900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361025(4-(2-amino-1H-benzo[d]imidazol-4-yl)-N1-(3-aminopr...)
Affinity DataIC50:  0.453nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361025(4-(2-amino-1H-benzo[d]imidazol-4-yl)-N1-(3-aminopr...)
Affinity DataIC50:  0.0390nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361025(4-(2-amino-1H-benzo[d]imidazol-4-yl)-N1-(3-aminopr...)
Affinity DataIC50:  0.0900nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent