BDBM361108 (R)-4-(2-amino-1H-benzo[d] imidazol-4-yl)-N1-(1- aminobutan-2-yl)-3-(2H- tetrazol-5-yl)benzene-1,2- disulfonamide::US10221163, Example 265::US10544130, Example 265

SMILES CC[C@H](CN)NS(=O)(=O)c1ccc(-c2cccc3[nH]c(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key InChIKey=HTZLMPQNWYVLLP-HNLKAFMCSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 361108   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361108((R)-4-(2-amino-1H-benzo[d] imidazol-4-yl)-N1-(1- a...)
Affinity DataIC50:  0.292nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361108((R)-4-(2-amino-1H-benzo[d] imidazol-4-yl)-N1-(1- a...)
Affinity DataIC50:  0.0240nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase()
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361108((R)-4-(2-amino-1H-benzo[d] imidazol-4-yl)-N1-(1- a...)
Affinity DataIC50:  0.0930nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361108((R)-4-(2-amino-1H-benzo[d] imidazol-4-yl)-N1-(1- a...)
Affinity DataIC50:  0.292nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361108((R)-4-(2-amino-1H-benzo[d] imidazol-4-yl)-N1-(1- a...)
Affinity DataIC50:  0.0240nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361108((R)-4-(2-amino-1H-benzo[d] imidazol-4-yl)-N1-(1- a...)
Affinity DataIC50:  0.0930nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent