BDBM361311 (S)-N1-(3-amino-2- hydroxypropyl)-4-(6-amino-5- methylpyridin-3-yl)-3-(2H- tetrazol-5-yl)benzene-1,2- disulfonamide::US10221163, Example 468::US10544130, Example 468

SMILES Cc1cc(cnc1N)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)NC[C@@H](O)CN

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 361311   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361311((S)-N1-(3-amino-2- hydroxypropyl)-4-(6-amino-5- me...)
Affinity DataIC50:  0.569nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361311((S)-N1-(3-amino-2- hydroxypropyl)-4-(6-amino-5- me...)
Affinity DataIC50:  0.133nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase()
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361311((S)-N1-(3-amino-2- hydroxypropyl)-4-(6-amino-5- me...)
Affinity DataIC50:  0.0870nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361311((S)-N1-(3-amino-2- hydroxypropyl)-4-(6-amino-5- me...)
Affinity DataIC50:  0.569nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361311((S)-N1-(3-amino-2- hydroxypropyl)-4-(6-amino-5- me...)
Affinity DataIC50:  0.133nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361311((S)-N1-(3-amino-2- hydroxypropyl)-4-(6-amino-5- me...)
Affinity DataIC50:  0.0870nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent