BDBM362336 US9834548, Example 125

SMILES CC(=O)N1CCC(Cn2cc(Nc3cc(NCc4cccc5ccsc45)c(nn3)C(N)=O)cn2)CC1

InChI Key InChIKey=NRTGWLADTAEEKV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362336   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM362336(US9834548, Example 125)
Affinity DataIC50:  550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM362336(US9834548, Example 125)
Affinity DataIC50:  5.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM362336(US9834548, Example 125)
Affinity DataIC50:  55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent