BDBM363402 N-(2-((5-bromo-4-((2-cyano-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzyl)oxy)-2-((3-cyanobenzyl)oxy)benzyl)amino)ethyl)acetamide::US10815208, Example 8::US9850225, Example 1315

SMILES CC(=O)NCCNCc1cc(Br)c(OCc2cccc(-c3ccc4OCCOc4c3)c2C#N)cc1OCc1cccc(c1)C#N

InChI Key InChIKey=OOQBRRLRXWBSIG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 363402   

TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM363402(N-(2-((5-bromo-4-((2-cyano-3-(2,3-dihydrobenzo[b][...)
Affinity DataIC50:  7.12nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363402(N-(2-((5-bromo-4-((2-cyano-3-(2,3-dihydrobenzo[b][...)
Affinity DataIC50:  5.30nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent