BDBM363754 US9855229, Compound 8

SMILES OC(=O)c1ccc(cc1)N1N=C(C2C=CC=NC12)C(=O)c1c(Cl)cccc1C1CC1

InChI Key InChIKey=CLZXFXLVWQYNLH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363754   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM363754(US9855229, Compound 8)
Affinity DataIC50:  1.98nMAssay Description:The assay is based on the principle that binding of the agonist to the RORγ causes a conformational change around helix 12 in the ligand binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent