BDBM36401 (2S)-2-Methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine, 14::CID24894153

SMILES C[C@H]1CN=C(N)c2sccc2O1

InChI Key InChIKey=TUOXPJFCQDMQOX-YFKPBYRVSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36401   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36401((2S)-2-Methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepi...)
Affinity DataIC50:  40nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36401((2S)-2-Methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepi...)
Affinity DataIC50:  80nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM36401((2S)-2-Methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepi...)
Affinity DataIC50:  80nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed