BDBM365584 US9868738, Example 20
SMILES C[C@@]1(NC(=N)c2cncnc2C1(F)F)c1sc(cc1Cl)-c1cccc(c1)-c1nnco1
InChI Key InChIKey=VZPHLMJKNSNKJV-LJQANCHMSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 365584
Affinity DataKi: 33.3nMAssay Description: Reagents: Na+-Acetate pH 5.0; 1% Brij-35; Glycerol; Dimethyl Sulfoxide (DMSO); Recombinant human soluble BACE1 catalytic domain (>95% pure); APP ...More data for this Ligand-Target Pair
Affinity DataKi: 118nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair