BDBM367841 (1H- benzo[d]imidazol- 4-yl)boronic acid::US10227331, Example 28::US10544130, Example 12

SMILES OB(O)c1cccc2[nH]cnc12

InChI Key InChIKey=UNWJCMBQRPPTIH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 367841   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367841((1H- benzo[d]imidazol- 4-yl)boronic acid | US10227...)
Affinity DataIC50:  1.33nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367841((1H- benzo[d]imidazol- 4-yl)boronic acid | US10227...)
Affinity DataIC50:  0.0490nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase()
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367841((1H- benzo[d]imidazol- 4-yl)boronic acid | US10227...)
Affinity DataIC50:  0.102nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367841((1H- benzo[d]imidazol- 4-yl)boronic acid | US10227...)
Affinity DataIC50:  0.316nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367841((1H- benzo[d]imidazol- 4-yl)boronic acid | US10227...)
Affinity DataIC50:  0.0430nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367841((1H- benzo[d]imidazol- 4-yl)boronic acid | US10227...)
Affinity DataIC50:  0.172nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In DepthDetails US Patent