BDBM37122 2-[(2-fluorobenzyl)thio]-5-(4-methylphenyl)-1,3,4-oxadiazole::2-[(2-fluorobenzyl)thio]-5-(p-tolyl)-1,3,4-oxadiazole::2-[(2-fluorophenyl)methylsulfanyl]-5-(4-methylphenyl)-1,3,4-oxadiazole::2-[(2-fluorophenyl)methylthio]-5-(4-methylphenyl)-1,3,4-oxadiazole::MLS000088696::SMR000072713::cid_750580

SMILES Cc1ccc(cc1)-c1nnc(SCc2ccccc2F)o1

InChI Key InChIKey=SIBQEDIQAPAOSH-UHFFFAOYSA-N

Data  5 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 37122   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37122(2-[(2-fluorobenzyl)thio]-5-(4-methylphenyl)-1,3,4-...)
Affinity DataEC50:  1.14E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37122(2-[(2-fluorobenzyl)thio]-5-(4-methylphenyl)-1,3,4-...)
Affinity DataEC50: >9.51E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37122(2-[(2-fluorobenzyl)thio]-5-(4-methylphenyl)-1,3,4-...)
Affinity DataEC50:  1.78E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37122(2-[(2-fluorobenzyl)thio]-5-(4-methylphenyl)-1,3,4-...)
Affinity DataEC50:  4.63E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM37122(2-[(2-fluorobenzyl)thio]-5-(4-methylphenyl)-1,3,4-...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay