BDBM371518 1-(2-Fluoroethyl)-N-[1-(fluoromethyl)cyclopropyl]-3-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]-2,4-dioxo-quinazoline-6-sulfonamide::US10239843, Example 629

SMILES Cc1nnc(Cn2c(=O)n(CCF)c3ccc(cc3c2=O)S(=O)(=O)NC2(CF)CC2)s1

InChI Key InChIKey=NLDZADGMCRXAIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371518   

TargetADP-ribosylhydrolase ARH3(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM371518(1-(2-Fluoroethyl)-N-[1-(fluoromethyl)cyclopropyl]-...)
Affinity DataIC50: >1.50E+5nMAssay Description:ARH3 In vitro selectivity assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length ARH3 (Enzo Life S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM371518(1-(2-Fluoroethyl)-N-[1-(fluoromethyl)cyclopropyl]-...)
Affinity DataIC50:  82nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent