BDBM371542 4-chloro-5-(((3R,5S)-1,5-dimethylpiperidin-3-yl)amino)-2-methylpyridazin-3(2H)-one::US10239861, Example 22

SMILES C[C@H]1C[C@H](CN(C)C1)Nc1cnn(C)c(=O)c1Cl

InChI Key InChIKey=MRZBXPNVEWAIIA-DTWKUNHWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371542   

TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Genetech

US Patent
LigandPNGBDBM371542(4-chloro-5-(((3R,5S)-1,5-dimethylpiperidin-3-yl)am...)
Affinity DataIC50:  21.5nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent