BDBM371635 (R)-4-(2-(1H-1,2,3-Triazol-1-yl)-4-(trifluoromethyl)phenyl)-N-(6-fluoropyridin-2-yl) chromane-7-sulfonamide::US10239869, Example 60
SMILES Fc1cccc(NS(=O)(=O)c2ccc3[C@H](CCOc3c2)c2ccc(cc2-n2ccnn2)C(F)(F)F)n1
InChI Key InChIKey=JKJIATXPNOQKCJ-MRXNPFEDSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 371635
Affinity DataIC50: 0.300nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells assessed as reduction in veratridine-induced depolarization preincubated for 15 to 20...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair