BDBM371739 4-(2-(4-fluorobutyl)-4-(trifluoromethyl)phenyl)-N-(pyrimidin-4-yl)chroman-7-sulfonamide::US10239869, Example 165

SMILES FCCCCc1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1ccncn1)C(F)(F)F

InChI Key InChIKey=DLJHITZLSYMCCA-HXUWFJFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371739   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM371739(4-(2-(4-fluorobutyl)-4-(trifluoromethyl)phenyl)-N-...)
Affinity DataIC50:  303nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM371739(4-(2-(4-fluorobutyl)-4-(trifluoromethyl)phenyl)-N-...)
Affinity DataIC50:  5nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent