BDBM371755 (S)-N-(6-fluoropyridin-2-yl)-4-(2-(((S)-tetrahydrofuran-3-yl)oxy)-4-(trifluoromethyl)phenyl)chroman-7-sulfonamide::US10239869, Example 181

SMILES Fc1cccc(NS(=O)(=O)c2ccc3[C@H](CCOc3c2)c2ccc(cc2O[C@H]2CCOC2)C(F)(F)F)n1

InChI Key InChIKey=JBKHFEPGILUJSA-WMZOPIPTSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371755   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM371755((S)-N-(6-fluoropyridin-2-yl)-4-(2-(((S)-tetrahydro...)
Affinity DataIC50:  0.900nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent