BDBM371774 (R)-4-(2-(5-fluoropyridin-2-yl)-4-(trifluoromethyl)phenyl)-N-(pyridazin-3-yl)chroman-7-sulfonamide::US10239869, Example 200

SMILES Fc1ccc(nc1)-c1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1cccnn1)C(F)(F)F

InChI Key InChIKey=DAVNSKGDQYFIMM-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371774   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM371774((R)-4-(2-(5-fluoropyridin-2-yl)-4-(trifluoromethyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM371774((R)-4-(2-(5-fluoropyridin-2-yl)-4-(trifluoromethyl...)
Affinity DataIC50:  0.5nMAssay Description:HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent