BDBM372607 N-[2-(4-Cyano-3-methyl-benzyl)-2H-[1,2,3]triazol-4-yl]-2-[6-(3,3-difluoro-pyrrolidin-1-yl)-pyridin-3-yl]-acetamide::US10246426, Example 167

SMILES Cc1cc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)ccc1C#N

InChI Key InChIKey=CFNMYDUPRIZRPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372607   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM372607(N-[2-(4-Cyano-3-methyl-benzyl)-2H-[1,2,3]triazol-4...)
Affinity DataIC50:  22nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent