BDBM374594 3-amino-5-[3-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-2-(hydroxymethyl)phenyl]-1H-indazole-7-carboxamide::US10246457, Example 3
SMILES CC(C)(C)c1cc(F)c2c(cnn(-c3cccc(-c4cc(C(N)=O)c5[nH]nc(N)c5c4)c3CO)c2=O)c1
InChI Key InChIKey=WYEFULDVWAKJFZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 374594
Affinity DataIC50: 16nMAssay Description:Btk enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (lime-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Btk enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (lime-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair