BDBM374616 US10246457, Example 25
SMILES CC(C)(C)c1cc(F)c2c(cnn(-c3cccc(c3CO)-c3cc(-c4cnn(c4)C4CCOCC4)c4[nH]nc(N)c4c3)c2=O)c1
InChI Key InChIKey=AFIBVCKOTVHAGO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 374616
Affinity DataIC50: 2.60nMAssay Description:Btk enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (lime-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Btk enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (lime-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair