BDBM376889 4-(aminomethyl)-1-[3,4-difluoro-5-(3-fluorophenoxy)phenyl]piperidin-4-ol (E19)::US9920053, Example 19
SMILES NCC1(O)CCN(CC1)c1cc(F)c(F)c(Oc2cccc(F)c2)c1
InChI Key InChIKey=RZKJUZNVAKAQIB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 376889
Affinity DataIC50: 9.55nMAssay Description:The affinity of the compounds of the invention to the human DAT or NET or SERT transporters is assessed by using the [3H]WIN-35,428 or [3H]nisoxetine...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Chronos Therapeutics
US Patent
Chronos Therapeutics
US Patent
Affinity DataIC50: 794nMAssay Description:The affinity of the compounds of the invention to the human DAT or NET or SERT transporters is assessed by using the [3H]WIN-35,428 or [3H]nisoxetine...More data for this Ligand-Target Pair
Affinity DataIC50: 363nMAssay Description:The affinity of the compounds of the invention to the human DAT or NET or SERT transporters is assessed by using the [3H]WIN-35,428 or [3H]nisoxetine...More data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:The affinity of the compounds of the invention to the human DAT or NET or SERT transporters is assessed by using the [3H]WIN-35,428 or [3H]nisoxetine...More data for this Ligand-Target Pair