BDBM377479 (S)-4-(3-(but-2-ynamido) piperidin-1-yl)-3-fluoro-7- (4-methylpiperazine-1- carbonyl)-9H-carbazole-1- carboxamide::US10266491, Example 172::US10676434, Example 172::US11053197, Example 172
SMILES CC#CC(=O)N[C@H]1CCCN(C1)c1c(F)cc(C(N)=O)c2[nH]c3cc(ccc3c12)C(=O)N1CCN(C)CC1
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 377479
Affinity DataIC50: 0.100nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 ATP (20 and...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair