BDBM37871 6-Ethyl-thieno[2,3-d]pyrimidin-4-ol::6-ethyl-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL6215::MLS000029626::SMR000009585::cid_645569

SMILES CCc1cc2c(nc[nH]c2=O)s1

InChI Key InChIKey=GXZAQJCUXCKYKB-UHFFFAOYSA-N

Data  5 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 37871   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37871(6-Ethyl-thieno[2,3-d]pyrimidin-4-ol | 6-ethyl-3H-t...)
Affinity DataIC50: >5.96E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37871(6-Ethyl-thieno[2,3-d]pyrimidin-4-ol | 6-ethyl-3H-t...)
Affinity DataIC50:  5.72E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM37871(6-Ethyl-thieno[2,3-d]pyrimidin-4-ol | 6-ethyl-3H-t...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM37871(6-Ethyl-thieno[2,3-d]pyrimidin-4-ol | 6-ethyl-3H-t...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM37871(6-Ethyl-thieno[2,3-d]pyrimidin-4-ol | 6-ethyl-3H-t...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro potency against TNF alpha induced expresion of intercellular adhesion molecule-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed