BDBM379986 US10829478, Compound 98::US9926281, Compound 471
SMILES CCc1cc(ccc1Cl)N1CCN(C[C@@H]1C)C(=O)CCC1(CC(O)=O)NC(=O)NC1=O
InChI Key InChIKey=GSHKFLCNIDFHJZ-JRTLGTJJSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 379986
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Galapagos
US Patent
Galapagos
US Patent
Affinity DataIC50: 852nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair