BDBM381057 1-(5-(tert-Butyl)-3-(dimethylphosphoryl)-2-methoxyphenyl)-3-(4-((2-((3,5-dimethoxyphenyl)-amino)pyrimidin-4-yl)oxy)naphthalen-1-yl)urea::US9890185, Example 18
SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(cc(c4OC)P(C)(C)=O)C(C)(C)C)c4ccccc34)n2)cc(OC)c1
InChI Key InChIKey=ZOJJTNITQOBIGV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 381057
Affinity DataIC50: 218nMAssay Description:Method 1: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determinin...More data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Method 1: The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining ...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Method 2: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to t...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair