BDBM381335 4-Chloro-3-methyl-1-(tetrahydro- pyran-4-yl)-1H-pyrazolo[3,4- b]pyridine-5-carboxylic acid (4- isopropyl-phenyl)-amide::US10272074, Example 168

SMILES CC(C)c1ccc(NC(=O)c2cnc3n(nc(C)c3c2Cl)C2CCOCC2)cc1

InChI Key InChIKey=VPWRKLYPONGENE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381335   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381335(4-Chloro-3-methyl-1-(tetrahydro- pyran-4-yl)-1H-py...)
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent