BDBM381368 4-chloro-N-(4-chlorophenyl)-1- (1,1-dioxidotetrahydro-2H- thiopyran-4-yl)-3-methyl-1H- pyrazolo[3,4-b]pyridine-5- carboxamide::US10272074, Example 201
SMILES Cc1nn(C2CCS(=O)(=O)CC2)c2ncc(C(=O)Nc3ccc(Cl)cc3)c(Cl)c12
InChI Key InChIKey=SLJKFGHINGDLIZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 381368
TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair