BDBM381368 4-chloro-N-(4-chlorophenyl)-1- (1,1-dioxidotetrahydro-2H- thiopyran-4-yl)-3-methyl-1H- pyrazolo[3,4-b]pyridine-5- carboxamide::US10272074, Example 201

SMILES Cc1nn(C2CCS(=O)(=O)CC2)c2ncc(C(=O)Nc3ccc(Cl)cc3)c(Cl)c12

InChI Key InChIKey=SLJKFGHINGDLIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381368   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381368(4-chloro-N-(4-chlorophenyl)-1- (1,1-dioxidotetrahy...)
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent