BDBM381369 4-chloro-1-(1,1-dioxidotetrahydro- 2H-thiopyran-4-yl)-3-methyl-N-(4- (trifluoromethyl)phenyl)-1H- pyrazolo[3,4-b]pyridine-5- carboxamide::US10272074, Example 202

SMILES Cc1nn(C2CCS(=O)(=O)CC2)c2ncc(C(=O)Nc3ccc(cc3)C(F)(F)F)c(Cl)c12

InChI Key InChIKey=QAPJGPMMLHTCDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 381369   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM381369(4-chloro-1-(1,1-dioxidotetrahydro- 2H-thiopyran-4-...)
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent