BDBM381372 4-Chloro-1-(1-isopropyl-piperidin- 4-yl)-1H-pyrazolo[3,4-b]pyridine- 5-carboxylic acid (4-isopropyl- phenyl)-amide::US10272074, Example 205
SMILES CC(C)N1CCC(CC1)n1ncc2c(Cl)c(cnc12)C(=O)Nc1ccc(cc1)C(C)C
InChI Key InChIKey=DGRMVMNBNIVOAR-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 381372
TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair