BDBM381374 4-chloro-1-(1-ethyl-piperidin-4-yl)- 1H-pyrazolo[3,4-b]pyridine-5- carboxylic acid (4-isopropyl- phenyl)-amide::US10272074, Example 207
SMILES CCN1CCC(CC1)n1ncc2c(Cl)c(cnc12)C(=O)Nc1ccc(cc1)C(C)C
InChI Key InChIKey=KCTIHUADSLMMIW-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 381374
TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair