BDBM381379 4-Chloro-1-(tetrahydro-pyran-4- yl)-1H-pyrazolo[3,4-b]pyridine-5- carboxylic acid (4-trifluoromethyl- phenyl)-amide::US10272074, Example 212
SMILES FC(F)(F)c1ccc(NC(=O)c2cnc3n(ncc3c2Cl)C2CCOCC2)cc1
InChI Key InChIKey=SOUWGHYVHQXDSC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 381379
TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair