BDBM381390 4-chloro-1-(tetrahydro-2H- thiopyran-4-yl)-N-(4- (trifluoromethyl)phenyl)-1H- pyrazolo[3,4-b]pyridine-5- carboxamide::US10272074, Example 223
SMILES FC(F)(F)c1ccc(NC(=O)c2cnc3n(ncc3c2Cl)C2CCSCC2)cc1
InChI Key InChIKey=SMKHADLRBLEEPC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 381390
TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair